Rampal, Poonam and Saini, H S and Raj, Mayil and Chimni, Swapandeep Singh and Chadha, Bhupinder Singh (2007) Enantiocomplementary reduction of 3-phenylthiopropan-2-one by Bacillus sp.: effect of medium components. Bioresource technology, 98 (3). pp. 725-8. ISSN 0960-8524
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Abstract
The enantioselectivity of the enzymes responsible for reduction of prochiral compound 3-phenylthiopropan-2-one was dependent on the concentration of yeast extract and glucose in the growth medium. Low concentrations of yeast extract (0.1-0.9% w/v) favored the formation of S-enantiomer (62% ee at 0.1% w/v yeast extract) of 3-phenylthiopropan-2-ol. However, R-enantiomer of the reduced product was formed when MSM was supplemented with yeast extract at a concentration of 1% (w/v) or more with a maximum ee of 85% at 2.0% (w/v) yeast extract supplement in the growth medium.
Item Type: | Article |
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Additional Information: | Copyright of this article belongs to Elsevier Science. |
Uncontrolled Keywords: | Asymmetric reduction; Enantioselectivity; Yeast extract |
Subjects: | Q Science > QR Microbiology |
Depositing User: | Dr. K.P.S.Sengar |
Date Deposited: | 17 Feb 2012 16:44 |
Last Modified: | 09 Jan 2015 11:20 |
URI: | http://crdd.osdd.net/open/id/eprint/1021 |
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