Sengupta, Chirantana and Ekka, Manjula and Arora, Saurabh and Dhaware, Prashant D and Chowdhury, Rukhsana and Raychaudhuri, Saumya (2017) Cross feeding of glucose metabolism byproducts of human gut isolates and probiotic strains affect survival of Vibrio cholerae. Gut pathogens, 9. p. 3. ISSN 1757-4749
Full text not available from this repository. (Request a copy)Abstract
converts glucose into either acid or the neutral end product acetoin and its survival in carbohydrate enriched media is linked to the nature of the byproducts produced. It has been demonstrated in this study that strain isolated from the gut of healthy human volunteers and the commonly used probiotic Nissle strain that metabolize glucose to acidic byproducts drastically reduce the survival of strains irrespective of their glucose sensitivity and acetoin production status. Accordingly, glucose transport mutants that produce lower amounts of acidic metabolites had little effect on the survival of in cocultures. Thus, cross feeding of byproducts of glucose metabolism by heterologous bacteria modulates the survival of in glucose rich medium suggesting that composition of the gut microbiota could influence the outcome of infection especially when glucose based ORS is administered.
| Item Type: | Article |
|---|---|
| Additional Information: | Open Access |
| Uncontrolled Keywords: | Cocultures; E. coli Nissle 1917; E. coli glucose transport mutants; V. cholerae survival |
| Subjects: | Q Science > QR Microbiology |
| Depositing User: | Dr. K.P.S.Sengar |
| Date Deposited: | 19 Sep 2018 08:10 |
| Last Modified: | 19 Sep 2018 08:10 |
| URI: | http://crdd.osdd.net/open/id/eprint/2120 |
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