Kalra, Rashi and Tiwari, Drishti and Dkhar, H Kitdorlang and Bhagyaraj, Ella and Kumar, Rakesh and Bhardwaj, Anshu and Gupta, Pawan (2021) Host factors subverted by Mycobacterium tuberculosis: Potential targets for host directed therapy. International reviews of immunology. ISSN 1563-5244
Full text not available from this repository. (Request a copy)Abstract
Despite new approaches in the diagnosis and treatment of tuberculosis (TB), it continues to be a major health burden. Several immunotherapies that potentiate the immune response have come up as adjuncts to drug therapies against drug resistant TB strains; however, there needs to be an urgent appraisal of host specific drug targets for improving their clinical management and to curtail disease progression. Presently, various host directed therapies (HDTs) exist (repurposed drugs, nutraceuticals, monoclonal antibodies and immunomodulatory agents), but these mostly address molecules that combat disease progression.
| Item Type: | Article |
|---|---|
| Additional Information: | The Copyright of this article belongs to Informa healthcare |
| Uncontrolled Keywords: | Host directed therapy (HDT); host epigenetic machinery; host transcription factors (TFs); host-pathogen interaction; tuberculosis (TB) |
| Subjects: | Q Science > QR Microbiology |
| Depositing User: | Dr. K.P.S.Sengar |
| Date Deposited: | 18 Apr 2022 06:05 |
| Last Modified: | 18 Apr 2022 06:05 |
| URI: | http://crdd.osdd.net/open/id/eprint/2951 |
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