Amino-terminal extension present in the methionine aminopeptidase type 1c of Mycobacterium tuberculosis is indispensible for its activity.

Kanudia, Pavitra and Mittal, Monica and Kumaran, Sangaralingam and Chakraborti, Pradip K (2011) Amino-terminal extension present in the methionine aminopeptidase type 1c of Mycobacterium tuberculosis is indispensible for its activity. BMC biochemistry, 12. p. 35. ISSN 1471-2091

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Abstract

Our findings unequivocally emphasized that N-terminal extension of MtMetAP1c contributes towards the functionality of the enzyme presumably by regulating active site residues through "action-at-a-distance" mechanism and we for the first time are reporting this unique function of the enzyme.

Item Type: Article
Uncontrolled Keywords: OPEN ACCESS
Subjects: Q Science > QD Chemistry
Depositing User: Dr. K.P.S.Sengar
Date Deposited: 09 Dec 2011 06:54
Last Modified: 09 Dec 2011 06:54
URI: http://crdd.osdd.net/open/id/eprint/461

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