Zeta potential based colorimetric immunoassay for the direct detection of diabetic marker HbA1c using gold nanoprobes.

Wangoo, Nishima and Kaushal, Jyotsna and Bhasin, K K and Mehta, S K and Suri, C Raman (2010) Zeta potential based colorimetric immunoassay for the direct detection of diabetic marker HbA1c using gold nanoprobes. Chemical communications (Cambridge, England), 46 (31). pp. 5755-7. ISSN 1364-548X

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Abstract

A one-step homogeneous colorimetric immunoassay format coupled with zeta potential measurements for determination of specific diabetic biomarker glycated hemoglobin (HbA1c) using functionalised gold nanoparticles as bioprobes is reported. The assay exhibited an excellent sensitivity based on absorbance and zeta potential measurements showing the dynamic response range from 0.001-0.004 mg mL(-1) for HbA1c with a detection limit of 0.0015 mg mL(-1).

Item Type:	Article
Additional Information:	Copyright of this article belongs to RSC Publishing
Subjects:	Q Science > QD Chemistry
Depositing User:	Dr. K.P.S.Sengar
Date Deposited:	08 Dec 2011 19:16
Last Modified:	08 Dec 2011 19:16
URI:	http://crdd.osdd.net/open/id/eprint/511

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