Neural simulation of an unsteady state continuous recombinant fermentation with imperfect mixing.

Patnaik, P R (1996) Neural simulation of an unsteady state continuous recombinant fermentation with imperfect mixing. Biotechnology Techniques, 10 (8). pp. 573-578. ISSN 0951-208X

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Official URL: http://dx.doi.org/10.1007/BF00157364

Abstract

A continuous fermentation based on a recombinant Escherichia coli strain producing tryptophan synthetase has been simulated by a back-propagation neural network. Data for the network were generated through known kinetics applied to a reactor model with an adjustable degree of macromixing of the broth. A network with just one hidden layer performed satisfactorily for both poor and good macromixing. The best performance was at an intermediate level of mixing, in the region of maximum productivity of the recombinant protein.

Item Type: Article
Additional Information: Copyright of this article belongs to Springer Science.
Subjects: Q Science > QR Microbiology
Depositing User: Dr. K.P.S.Sengar
Date Deposited: 27 Jan 2012 15:08
Last Modified: 12 Jan 2015 04:15
URI: http://crdd.osdd.net/open/id/eprint/744

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