REFERENCES


Gene Name Pubmed ID Classification Sample Location Remark
DAPK1 17971771MethylationVU University Medical Center in AmerstdamDAPK1 is significantly methylated with frequency 56.3% in squamous cell carcinomas.  
DAPK1 17548682MethylationUniversity of Dakar, SenegalDAPK1 is hypermethylated and thus it can be a potential and a sensitive molecular marker in urine sample from cervical cancer patients. DAPK1 is more methylated in 49% of ICC and 28% of CIN2-3/CIS.  
DAPK1 15713962MethylationCommunity Health Clinic in Dakar, Senegal.The frequency of hypermethylation of DAPK1 increased statistically significantly with increasing severity of neoplasia present in the cervical biopsy (P<0.001)  
DAPK1 12773202MethylationInstituto Nacional de Cancerologia, Colombia and Department of Obstetrics and Gynecology of Friedrich Schiller University, Jena, GermanyThe frequency of methylation of DAPK1 gene promoter is 43.3%.  
DAPK1 20208141MethylationPathology Archives of the University Medical Center Groningen (UMCG).Methylation of DAPK1 increases during cervical carcinogenesis and thus is reported as one of the best markers to distinguish normal/LSIL from HSIL/cancer lesions.  
DAPK1 16331610MethylationGynecologic Oncology Division of Seoul National University HospitalMethylation of DAPK gene is more frequently in AC than SCC (77.4%,P=0.005)  
DAPK1 19513524MethylationColposcopy Unit of University Hospital of Larissa; Greece.DAPK promoter methylation has been found in 66.7% of premalignant and 57.4% of cancer cases.  
DAPK1 14760078MethylationDepartment of Obsterics and Gynecology, Innsbruck University Hospital.Aberrant methylation of CpG island within the promoter regions.  
DAPK1 11448914MethylationSamsung Cheil Hospital, Seoul, KoreaDAPK is significantly more methylated with frequency 61% in squamous cell carcinoma  
DAPK1 12702579MethylationAnatomical Pathology Department of the City of Hope National Medical Center.Aberrant methylation of CpG island within the promoter regions has been observed in the 25-50% of the tumors.  
DAPK1 16736496MethylationClinic of the University Medical Center Groningen.DAPK promoter methylation was significantly more methylated in cancers than control  
DAPK1 19836067MethylationChonnam National University Hwasun HospitalThe trend of methylation of this gene is increasing with increasing severity of cervical squamous lesions (p<0.001).  
DAPK1 15589597MethylationDepartment of Obstertics and Gynecology, Seoul national University Hospital.Frequency of methylation of this gene is found to be 73.2%.  
DAPK1 18181097MethylationJohns Hopkins Hospital.Methylation of this gene was detected in 10 (25.6%) of 39 HSIL Pap tests compared with 2(3.3%) of 60 combined NILM/LSIL Pap tests.  
DAPK1 16803511MethylationBusan Paik Hospital, Inje University, Busan, South Korea. The frequencies of promoter methylation of p16, DAPK, CDH1, and TIMP-3 in cervical cancer were 57%, 44.9%, 52.6%, and 9%, respectively  
DAPK1 16928264Methylation-Incidence of hypermethylation for DAPK, MGMT, p16 and PTEN in cervical cancer was 56.7%, 25.2%, 16.5% and 15.7% respectivel  
DAPK1 15099958MethylationQueen Mary Hospital, Hong Kong.Promotor CpG island methylation of DAPK, p16, and MGMT was detectable, respectively, in 60%, 28.2%, and 18.8% of cases of cervical tumor DNA, and in 40%, 10%, and 7.5% of cases of patients' plasma DNA  
DAPK1 14767518Methylation-reduced DAPK expression and methylation of the DAPK promoter may be involved in carcinogenesis of human uterine and ovarian tissues.  
DAPK1 19755648MethylationColoscopy Clinic, Jessop Wing or the Oncology Department of the Royal hallamshire Hospital, Sheffield.Tumor suppressor gene DAPK exhibited a significantly increased frequency of promoter methylation with progressively more severe cervical neoplasia (P < 0.05). HIC1 gene is reported to be a potential biomarker of cervical neoplasia