REFERENCES


Gene Name Pubmed ID Classification Sample Location Remark
HIC1 12773202MethylationInstituto Nacional de Cancerologia, Colombia and Department of Obstetrics and Gynecology of Friedrich Schiller University, Jena, GermanyThe frequency of methylation of HIC1 gene promoter is 22.2%.  
HIC1 19755648MethylationColoscopy Clinic, Jessop Wing or the Oncology Department of the Royal hallamshire Hospital, Sheffield.Tumor suppressor gene HIC1 exhibited a significantly increased frequency of promoter methylation with progressively more severe cervical neoplasia (P < 0.05). HIC1 gene is reported to be a potential biomarker of cervical neoplasia  
HIC1 11448914MethylationSamsung Cheil Hospital, Seoul, KoreaHypermethylation of HIC-1 promoter in adenocarcinoma is at a statistically higher significant frequency than in squamous cell carcinoma.  
HIC1 12702579MethylationAnatomical Pathology Department of the City of Hope National Medical Center.Aberrant methylation of CpG island within the promoter regions has been observed in the 25-50% of the tumors.  
HIC1 19836067MethylationChonnam National University Hwasun HospitalThe trend of methylation of this gene is increasing with increasing severity of cervical squamous lesions (p<0.001).