Gene Name |
Pubmed ID |
Classification |
Sample Location |
Remark |
HIC1 | 12773202 | Methylation | Instituto Nacional de Cancerologia, Colombia and Department of Obstetrics and Gynecology of Friedrich Schiller University, Jena, Germany | The frequency of methylation of HIC1 gene promoter is 22.2%.   |
HIC1 | 19755648 | Methylation | Coloscopy Clinic, Jessop Wing or the Oncology Department of the Royal hallamshire Hospital, Sheffield. | Tumor suppressor gene HIC1 exhibited a significantly increased frequency of promoter methylation with progressively more severe cervical neoplasia (P < 0.05). HIC1 gene is reported to be a potential biomarker of cervical neoplasia   |
HIC1 | 11448914 | Methylation | Samsung Cheil Hospital, Seoul, Korea | Hypermethylation of HIC-1 promoter in adenocarcinoma is at a statistically higher significant frequency than in squamous cell carcinoma.   |
HIC1 | 12702579 | Methylation | Anatomical Pathology Department of the City of Hope National Medical Center. | Aberrant methylation of CpG island within the promoter regions has been observed in the 25-50% of the tumors.   |
HIC1 | 19836067 | Methylation | Chonnam National University Hwasun Hospital | The trend of methylation of this gene is increasing with increasing severity of cervical squamous lesions (p<0.001).   |