REFERENCES


Gene Name Pubmed ID Classification Sample Location Remark
MDM2 17306351OverexpressionClinic of Obstetrics and Gynaecology at the Medical University of Vienna, Austria.MDM2 protoncogene showed a 4.62 fold higher increase in malignant cervical squamous cells  
MDM2 18813814UpregulationDepartment of Obsterics and Gynaecology of the University Hospital of Heraklion, CreteThis gene is found to be upregulated 88% and 73% in HSIL and LSIL cases.  
MDM2 20200430--The combination of high levels of MDM2 with the G-allele of SNP309 can severley weaken the p53 tumor suppressor pathway resulting in higher mutation rate, less efficient DNA repair and reduced apoptosis.