Gene Name |
Pubmed ID |
Classification |
Sample Location |
Remark |
RARB | 17548682 | Methylation | University of Dakar, Senegal | It is reported to be hypermethylated and thus it can be a potential and sensitive molecular marker in urine samples from women with ICC or CIN-2,3/CIS. RARB is methylated in 40% of ICC and 4% of CIN2-3/CIS.   |
RARB | 12773202 | Methylation | Instituto Nacional de Cancerologia, Colombia and Department of Obstetrics and Gynecology of Friedrich Schiller University, Jena, Germany | The frequency of methylation of RARB gene promoter is 33.3%.   |
RARB | 17971771 | Methylation | VU University Medical Center in Amerstdam | RARB is significantly methylated in both squamous cell carcinoma and adenocarcinoma cells.   |
RARB | 17467893 | Methylation | Samsung Medical School, Seoul, Korea | The high frequency of promoter hypermethylation in cervical carcinoma suggests that they play a role in the development of cervical squamous cell carcinoma. The frequency of hypermethylation for RARB in cervical carcinoma have been reported to be 33-60%.   |
RARB | 14760078 | Methylation | Department of Obsterics and Gynecology, Innsbruck University Hospital. | Aberrant methylation of CpG island within the promoter regions.   |
RARB | 10389939 | Downregulation | Department of Pathology, University of Texas, M.D. Anderson Cancer Research Centre | RARB is referred to have reduced expression by 64.7% in CIN lesions as compared to normal cell   |
RARB | 11297252 | Methylation | Parkland Health and Hospital System, Dallas, Texas. | The methylation RARB gene is an early event in cervical cancer.   |
RARB | 12702579 | Methylation | Anatomical Pathology Department of the City of Hope National Medical Center. | Aberrant methylation of CpG island within the promoter regions has been observed in the 25-50% of the tumors. .   |
RARB | 15713962 | Methylation | Community Health Clinic in Dakar, Senegal. | The frequency of hypermethylation of RARB increased statistically significantly with increasing severity of neoplasia present in the cervical biopsy (P<0.001)   |
RARB | 16736496 | Methylation | Clinic of the University Medical Center Groningen. | RARB promoter methylation was significantly more methylated in cancers than control   |
RARB | 19836067 | Methylation | Chonnam National University Hwasun Hospital | The trend of methylation of this gene is increasing with increasing severity of cervical squamous lesions (p<0.001).   |