REFERENCES


Gene Name Pubmed ID Classification Sample Location Remark
RARB 17548682MethylationUniversity of Dakar, SenegalIt is reported to be hypermethylated and thus it can be a potential and sensitive molecular marker in urine samples from women with ICC or CIN-2,3/CIS. RARB is methylated in 40% of ICC and 4% of CIN2-3/CIS.  
RARB 12773202MethylationInstituto Nacional de Cancerologia, Colombia and Department of Obstetrics and Gynecology of Friedrich Schiller University, Jena, GermanyThe frequency of methylation of RARB gene promoter is 33.3%.  
RARB 17971771MethylationVU University Medical Center in AmerstdamRARB is significantly methylated in both squamous cell carcinoma and adenocarcinoma cells.  
RARB 17467893MethylationSamsung Medical School, Seoul, KoreaThe high frequency of promoter hypermethylation in cervical carcinoma suggests that they play a role in the development of cervical squamous cell carcinoma. The frequency of hypermethylation for RARB in cervical carcinoma have been reported to be 33-60%.  
RARB 14760078MethylationDepartment of Obsterics and Gynecology, Innsbruck University Hospital.Aberrant methylation of CpG island within the promoter regions.  
RARB 10389939DownregulationDepartment of Pathology, University of Texas, M.D. Anderson Cancer Research CentreRARB is referred to have reduced expression by 64.7% in CIN lesions as compared to normal cell  
RARB 11297252MethylationParkland Health and Hospital System, Dallas, Texas.The methylation RARB gene is an early event in cervical cancer.  
RARB 12702579MethylationAnatomical Pathology Department of the City of Hope National Medical Center.Aberrant methylation of CpG island within the promoter regions has been observed in the 25-50% of the tumors. .  
RARB 15713962MethylationCommunity Health Clinic in Dakar, Senegal.The frequency of hypermethylation of RARB increased statistically significantly with increasing severity of neoplasia present in the cervical biopsy (P<0.001)  
RARB 16736496MethylationClinic of the University Medical Center Groningen.RARB promoter methylation was significantly more methylated in cancers than control  
RARB 19836067MethylationChonnam National University Hwasun HospitalThe trend of methylation of this gene is increasing with increasing severity of cervical squamous lesions (p<0.001).