Summary:
The method can identify and predict HLA binding regions from antigen sequence. The method allows identification & prediction for 87 alleles, out of which 51 belong to Class I and 36 belongs to Class II.The output format (HTML MAPPING) will assist users in locating promiscuous HLA binders, which can be most putative vaccine candidates.
Paste Your Protein Sequence
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or
Upload Sequence File
Choose Format of input sequence
Amino acids in single letter code
Standard sequence format[PIR/FASTA/EMBL etc.]
Select HLA allele
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Class I
ALL
HLA-A1
HLA-A2
HLA-A*0201
HLA-A*0202
HLA-A*0203
HLA-A*0205
HLA-A*0206
HLA-A2.1
HLA-A3
HLA-A*0301
HLA-A11
HLA-A*1101
HLA-A20
HLA-A24
HLA-A*2402
HLA-A31
HLA-A*3101
HLA-A*3302
HLA-A68.1
HLA-A*6801
HLA-A*6802
HLA-B7
HLA-B*0702
HLA-B8
HLA-B14
HLA-B27
HLA-B*2702
HLA-B*2705
HLA-B*3501
HLA-B*3701
HLA-B*3801
HLA-B*3901
HLA-B*3902
HLA-B40
HLA-B*4403
HLA-B*51
HLA-B*5101
HLA-B*5102
HLA-B*5103
HLA-B*5201
HLA-B*5301
HLA-B*5401
HLA-B*5801
HLA-B60
HLA-B61
HLA-B62
HLA-B*2706
HLA-B35
HLA-A*0204
HLA-B*2703
HLA-B*2704
HLA-B*2902
HLA-A*3301
HLA-B44
Class II
ALL
HLA-DRB1*0101
HLA-DRB1*0102
HLA-DRB1*0301
HLA-DRB1*0305
HLA-DRB1*0306
HLA-DRB1*0307
HLA-DRB1*0308
HLA-DRB1*0309
HLA-DRB1*0311
HLA-DRB1*0401
HLA-DRB1*0402
HLA-DRB1*0404
HLA-DRB1*0405
HLA-DRB1*0408
HLA-DRB1*0410
HLA-DRB1*0421
HLA-DRB1*0423
HLA-DRB1*0426
HLA-DRB1*0701
HLA-DRB1*0703
HLA-DRB1*0801
HLA-DRB1*0802
HLA-DRB1*0804
HLA-DRB1*0806
HLA-DRB1*0813
HLA-DRB1*0817
HLA-DRB1*1101
HLA-DRB1*1102
HLA-DRB1*1104
HLA-DRB1*1106
HLA-DRB1*1107
HLA-DRB1*1114
HLA-DRB1*1120
HLA-DRB1*1121
HLA-DRB1*1128
HLA-DRB1*1301
HLA-DRB1*1302
HLA-DRB1*1304
HLA-DRB1*1305
HLA-DRB1*1307
HLA-DRB1*1311
HLA-DRB1*1321
HLA-DRB1*1322
HLA-DRB1*1323
HLA-DRB1*1327
HLA-DRB1*1328
HLA-DRB1*1501
HLA-DRB1*1502
HLA-DRB1*1506
HLA-DRB5*0101
HLA-DRB5*0105
BOTH
Method
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Identification of Experimental Binders
Predict Binders
Both
Prediction Parameters
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Threshold
1%
2%
3%
4%
5%
6%
7%
8%
9%
10%
Display Format
HTML Mapping
Tabular
Display Top
Peptides