| HMRbase accession number | 1357 |
| PubChem ID | 5280878 |
| Hormone name | Leukotriene D4 |
| Description | One of the biologically active principles of SRS-A. It is generated from LEUKOTRIENE C4 after partial hydrolysis of the peptide chain, i.e., cleavage of the gamma-glutamyl portion. Its biological actions include stimulation of vascular and nonvascular smooth muscle, and increases in vascular permeability. (From Dictionary of Prostaglandins and Related Compounds, 1990) |
| Synonyms | leukotriene D4 Leukotriene D4 LTD4 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11E,14Z-eicosatetraenoi (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9- pentadecatetraenyl)-L-cysteinyl)glycine |
| Molecular weight | 496.66 |
| Molecular formula | C25H40N2O6S |
| IUPAC Name | (5S,6R,7E,9E,11Z,14Z)-6-[(2R)-2-amino-3-(carboxymethylamino)-3-oxopropyl]sulfanyl-5-hydroxyicosa-7,9,11,14-tetraenoicacid
|
| Canonical smiles | CCCCCC=CCC=CC=CC=CC(C(CCCC(=O)O)O)SCC(C(=O)NCC(=O)O)N |
| Isomeric smiles | CCCCCC=C/CC=C/C=C/C=C/[C@H]([C@H](CCCC(=O)O)O)SC[C@@H](C(=O)NCC(=O)O)N
|
| Structure |
| PDB file |
| SDF file |
| MOL file |
| PDB ID | N/A |
| KEGG ID | C05951 |
| HMDB ID | N/A |
| Melting Point | N/A |
| Log P | N/A |
| Water Solubility | N/A |
| DrugBank ID | N/A |
| Drugpedia | wiki |
| Receptor | Q9NS75 Detail in HMRbase
Q9Y271 Detail in HMRbase
|
| Comments | |
| References | Endonet |
A database of hormones and their receptors