A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 10027 |
| Swiss-prot Accession number | P01178 (Sequence in FASTA format) |
| Description | Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin(Ocytocin); Neurophysin 1]. |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Secreted |
| Developmental Stage | N/A |
| Similarity | Belongs to the vasopressin/oxytocin family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland |
| Protein Length | 125 Amino acids |
| Molecular weight | 12722 |
| References | 1 PubMed abstract 3768139 2 PubMed abstract 2991279 3 Grunwald W.C. Jr., Cool D.R.; "Lack of sequence polymorphism in the oxytocin gene of autisticpatients."; Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 11780052 5 PubMed abstract 15489334 6 PubMed abstract 2249637 7 PubMed abstract 4065330 8 PubMed abstract 6574452 9 PubMed abstract 7262323 10 PubMed abstract 13591312 |
| Domain Name | Hormone_5 |
| Hormone Name | Oxytocin |
| Mature Hormone Sequence | CYIQNCPLG |
| Position of mature hormone in Pre-Hormone protein | 9 Residues from position (20-28) |
| Receptor | P30559
Detail in HMRbase |
| Gene ID | 5020 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |