A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21436 |
| Swiss-prot Accession number | P07812 (Sequence in FASTA format) |
| Description | Progesterone receptor;PR;Alternative Name: Nuclear receptor subfamily 3 group C member 3 |
| Source organism | Gallus gallus (Chicken) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Oviduct and bursa of Fabricius. |
| Post translational modification | Phosphorylation of Ser-529 is sharply incrased upon progesterone treatment, whereas phosphorylation of Ser-210 and Ser-259 is modestly induced by progesterone. |
| Function | The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. |
| Protein Length | 786 Amino acids |
| Molecular weight | 85744 |
| Domain Name | Hormone_recep Prog_receptor zf-C4 |
| References | 1 PubMed abstract 3443098 2 PubMed abstract 3153474 3 PubMed abstract 2303488 4 PubMed abstract 2426779 5 PubMed abstract 3453892 6 PubMed abstract 3653503 7 PubMed abstract 2398063 8 PubMed abstract 2426697 9 PubMed abstract 2760059 10 PubMed abstract 7877616 11 PubMed abstract 8662804 |
| Hormone | Detail in HMRbase Detail in HMRbase |
| Gene ID | 396198 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |