A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 11425 |
| Swiss-prot Accession number | P20396 (Sequence in FASTA format) |
| Description | Thyroliberin precursor [Contains: Prothyroliberin; Thyroliberin(Thyrotropin-releasing hormone) (TRH) (Thyrotropin-releasing factor)(TRF) (TSH-releasing factor) (Protirelin)]. |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Secreted protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the TRH family. |
| Tissue Specificity | Hypothalamus |
| Post translational modification | N/A |
| Function | Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems |
| Protein Length | 242 Amino acids |
| Molecular weight | 27404 |
| References | 1 PubMed abstract 2126343 2 PubMed abstract 15489334 |
| Domain Name | TRH |
| Hormone Name | Thyroliberin |
| Mature Hormone Sequence | QHP |
| Position of mature hormone in Pre-Hormone protein | 3 Residues from position (84-86) |
| Receptor | P34981
Detail in HMRbase |
| Gene ID | 7200 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |