A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20994 |
| Swiss-prot Accession number | P21729 (Sequence in FASTA format) |
| Description | Gastrin-releasing peptide receptor (GRP-R) (GRP-preferring bombesinreceptor). |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Cell membrane; Multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | Brain (hypothalamus), pancreatic acinar cells, and fibroblasts. |
| Post translational modification | N/A |
| Function | Receptor for gastrin releasing peptide (GRP). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Protein Length | 384 Amino acids |
| Molecular weight | 43215 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 1671171 2 PubMed abstract 1707129 3 PubMed abstract 8391296 |
| Hormone | Q8R1I2 Detail in HMRbase |
| Gene ID | 14829 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |