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Peptide Hormone

Search Result - 1

HMRbase accession number	11429
Swiss-prot Accession number	P24393 (Sequence in FASTA format)
Description	Gastrin-releasing peptide precursor (GRP) [Contains: Neuromedin-C(GRP-10)].
Source organism	Rattus norvegicus (Rat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the bombesin/neuromedin-B/ranatensin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression, long-term potentiation, and amygdala-dependent memory for fear
Protein Length	147 Amino acids
Molecular weight	15817
References	1  PubMed abstract 2843761
Domain Name	Bombesin
Hormone Name	Gastrin-releasing peptide
Mature Hormone Sequence	APVSTGAGGGTVLAKMYPRGSHWAVGHLM
Position of mature hormone in Pre-Hormone protein	29 Residues from position (24-52)
Receptor	P52500    Detail in HMRbase
Gene ID	171101
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 2

HMRbase accession number	11430
Swiss-prot Accession number	P24393 (Sequence in FASTA format)
Description	Gastrin-releasing peptide precursor (GRP) [Contains: Neuromedin-C(GRP-10)].
Source organism	Rattus norvegicus (Rat)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the bombesin/neuromedin-B/ranatensin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	147 Amino acids
Molecular weight	15817
References	1  PubMed abstract 2843761
Domain Name	Bombesin
Hormone Name	Neuromedin-C
Mature Hormone Sequence	GSHWAVGHLM
Position of mature hormone in Pre-Hormone protein	10 Residues from position (43-52)
Receptor	P52500    Detail in HMRbase
Gene ID	171101
PDB ID	N/A
Drugpedia	wiki
Comments