A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 21022 |
| Swiss-prot Accession number | P32082 (Sequence in FASTA format) |
| Description | Growth hormone-releasing hormone receptor precursor (GHRH receptor)(GRF receptor) (GRFR). |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 2 family. |
| Tissue Specificity | Pituitary gland. |
| Post translational modification | N/A |
| Function | Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion. |
| Protein Length | 423 Amino acids |
| Molecular weight | 47044 |
| Domain Name | 7tm_2 HRM |
| References | 1 PubMed abstract 1334535 2 PubMed abstract 8391647 |
| Hormone | P16043 Detail in HMRbase |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |