A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21035 |
| Swiss-prot Accession number | P34999 (Sequence in FASTA format) |
| Description | Growth hormone-releasing hormone receptor precursor (GHRH receptor)(GRF receptor) (GRFR). |
| Source organism | Sus scrofa (Pig) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 2 family. |
| Tissue Specificity | Pituitary gland. Also detected in the lymphocytes and thymocytes. |
| Post translational modification | N/A |
| Function | Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion. |
| Protein Length | 423 Amino acids |
| Molecular weight | 47200 |
| Domain Name | 7tm_2 HRM |
| References | 1 PubMed abstract 8413847 2 Hazem H.A., Zhang X., Smith D.P., Heiman M.L., Hsiung H.M.; Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases. |
| Hormone | P01287 Detail in HMRbase Q9GKY5 Detail in HMRbase |
| Gene ID | 397100 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |