A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21049 |
| Swiss-prot Accession number | P47872 (Sequence in FASTA format) |
| Description | Secretin receptor precursor (SCT-R). |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 2 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
| Protein Length | 440 Amino acids |
| Molecular weight | 50207 |
| Domain Name | 7tm_2 HRM |
| References | 1 PubMed abstract 7864894 2 PubMed abstract 7612008 3 PubMed abstract 7700244 4 Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 5 King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases. |
| Hormone | P09683 Detail in HMRbase |
| Gene ID | 6344 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |