| HMRbase accession number | 21050 |
| Swiss-prot Accession number | P49059 (Sequence in FASTA format) |
| Description | Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor). |
| Source organism | Sus scrofa (Pig) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats. |
| Tissue Specificity | N/A |
| Post translational modification | N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone (By similarity). |
| Function | Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
| Protein Length | 695 Amino acids |
| Molecular weight | 78173 |
| Domain Name | N/A |
| References | 1 PubMed abstract 7590277
2 Wang Y.F., Meyer K.B., Schmidt K., Wan S.J., Degen S.J.F.,la Barbera A.R.; "Porcine follicle-stimulating hormone receptor."; Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
3 PubMed abstract 7590277
4 Wang Y.F., Meyer K.B., Schmidt K., Wan S.J., Degen S.J.F.,la Barbera A.R.; "Porcine follicle-stimulating hormone receptor."; Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
|
| Hormone | P01219 Detail in HMRbase
P01228 Detail in HMRbase
|
| Gene ID | 397679 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | |
A database of hormones and their receptors