A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21235 |
| Swiss-prot Accession number | P49880 (Sequence in FASTA format) |
| Description | RecName: Ecdysone receptor;Alternative Name: Ecdysteroid receptor;Alternative Name: 20-hydroxy-ecdysone receptor;20E receptor;Alternative Name: EcRH;AaEcR;Alternative Name: Nuclear receptor subfamily 1 group H member 1; |
| Source organism | Aedes aegypti (Yellowfever mosquito) |
| Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;Culicinae; Culicini; Aedes; Stegomyia. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | A peak level expression is seen in the fat body of previtellogenic female mosquitos at one and two days after eclosion, levels fall three-fold at three days posteclosion. |
| Post translational modification | N/A |
| Function | Receptor for ecdysone. Binds to ecdysone response elements (ECRES). |
| Protein Length | 776 Amino acids |
| Molecular weight | 83645 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 7711747 2 PubMed abstract 12385823 3 PubMed abstract 17510324 |
| Hormone | Detail in HMRbase |
| Gene ID | 5572184 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |