A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21465 |
| Swiss-prot Accession number | P51448 (Sequence in FASTA format) |
| Description | Nuclear receptor ROR-alpha;Alternative Name: Retinoid-related orphan receptor-alpha;Alternative Name: Nuclear receptor RZR-alpha;Alternative Name: Nuclear receptor subfamily 1 group F member 1 |
| Source organism | Mus musculus (Mouse) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular location | Nucleus (Probable) |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Expressed in cerebellum, lung and kidney. |
| Post translational modification | N/A |
| Function | Orphan nuclear receptors. Binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. This isomer binds to the consensus sequence [AGT][TA][AT][TA]C[AT]AGGTCA. |
| Protein Length | 523 Amino acids |
| Molecular weight | 58845 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 8602221 2 PubMed abstract 7935491 3 PubMed abstract 9226375 4 PubMed abstract 8750880 5 PubMed abstract 15489334 |
| Hormone | Detail in HMRbase |
| Gene ID | 19883 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |