A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21059 |
| Swiss-prot Accession number | P70536 (Sequence in FASTA format) |
| Description | Oxytocin receptor (OT-R). |
| Source organism | Rattus norvegicus (Rat) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
| Subcellular location | Cell membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. |
| Protein Length | 388 Amino acids |
| Molecular weight | 42869 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 7816817 2 Zingg H.H.; Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases. 3 Terry R., Mullins D.; "Rat oxytocin receptor gene nucleotide sequence."; Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 7816817 5 Zingg H.H.; Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases. 6 Terry R., Mullins D.; "Rat oxytocin receptor gene nucleotide sequence."; Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. 7 PubMed abstract 7816817 8 Zingg H.H.; Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases. 9 Terry R., Mullins D.; "Rat oxytocin receptor gene nucleotide sequence."; Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. |
| Hormone | P01179 Detail in HMRbase |
| Gene ID | 25342 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |