A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21078 |
| Swiss-prot Accession number | Q28005 (Sequence in FASTA format) |
| Description | Lutropin-choriogonadotropic hormone receptor precursor (LH/CG-R) (LSH-R) (Luteinizing hormone receptor). |
| Source organism | Bos taurus (Bovine) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 6 LRR (leucine-rich) repeats. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
| Protein Length | 701 Amino acids |
| Molecular weight | 78456 |
| Domain Name | 7tm_1 LRR_1 |
| References | 1 Lussier J.G., Houde A., Ethier J.-F., Silversides D.W.; Submitted (MAR-1995) to the EMBL/GenBank/DDBJ databases.
2 Kawate N., Tamada H., Inaba T., Sawada T.; "Expression of a cloned full-length cDNA encoding bovine luteinizinghormone receptor in COS-7 cells."; Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 9532424 |
| Hormone | P01217 Detail in HMRbase P04651 Detail in HMRbase |
| Gene ID | 281900 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |