A database of hormones and their receptors |
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| HMRbase accession number | 10331 |
| Swiss-prot Accession number | Q6X4W1 (Sequence in FASTA format) |
| Description | Nasal embryonic luteinizing hormone-releasing hormone factor (Nasalembryonic LHRH factor). |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Cell membrane; peripheral membrane protein (By similarity). Note=Found on the outside of the LHRH cell membrane and axons projecting from the olfactory pit and epithelium (By similarity) |
| Developmental Stage | N/A |
| Similarity | N/A |
| Tissue Specificity | Highly expressed in adult and fetal brain, testis and kidney |
| Post translational modification | N/A |
| Function | Influences outgrowth of olfactory axons and migration of LHRH neurons |
| Protein Length | 530 Amino acids |
| Molecular weight | 60143 |
| References | 1 PubMed abstract 15362570 2 PubMed abstract 14702039 3 PubMed abstract 15164053 4 PubMed abstract 15489334 5 Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases. 6 PubMed abstract 16565220 |
| Domain Name | N/A |
| Hormone Name | Nasal embryonic luteinizing hormone-releasing hormone factor |
| Mature Hormone Sequence | MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHDGSPEMQPAPQNKRRLSLVSNGCYEGSLSEEPSIRKPAGEGPQPRVYTISGEPALLPSPEAEAIELAVVKGRRQRHPHHHSQPLRASPGGSREDVSRPCQSWAGSRQGSKECPGCAQLAPGPTPRAFGLDQPPLPETSGRRKKLERMYSVDRVSDDIPIRTWFPKENLFSFQTATTTMQAISVFRGYAERKRRKRENDSASVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPMKADTSHDSRDSSDLQSSHCTLDEAFEDLDWDTEKGLEAVACDTEGFVPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIERKLNVYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYRVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL |
| Position of mature hormone in Pre-Hormone protein | 530 Residues from position (1-530) |
| Receptor | P30968
Detail in HMRbase |
| Gene ID | 26012 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |