A database of hormones and their receptors

Peptide Hormone

HMRbase accession number	11504
Swiss-prot Accession number	Q6ZXC3 (Sequence in FASTA format)
Description	Thyroliberin precursor [Contains: Prothyroliberin; Thyroliberin(Thyrotropin-releasing hormone) (TRH) (Thyrotropin-releasing factor)(TRF) (TSH-releasing factor) (Protirelin); Thyroliberin-like].
Source organism	Gallus gallus (Chicken)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the TRH family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems
Protein Length	260 Amino acids
Molecular weight	30337
References	1 PubMed abstract 16079264 2 Aoki Y., Masuda T., Yasuo S., Yoshimura T., Ebihara S., Iigo M.,Yanagisawa T.; "Molecular cloning of prepro-thyrotropin-releasing hormone cDNA andits expression in the brain of chicken (Gallus gallus)."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
Domain Name	TRH
Hormone Name	Thyroliberin
Mature Hormone Sequence	QHP
Position of mature hormone in Pre-Hormone protein	3 Residues from position (79-81)
Receptor	O93603 Detail in HMRbase
Gene ID	414344
PDB ID	N/A
Drugpedia	wiki
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