| HMRbase accession number | 21157 |
| Swiss-prot Accession number | Q8TDU9 (Sequence in FASTA format) |
| Description | Relaxin-3 receptor 2 (Relaxin family peptide receptor 4) (G-proteincoupled receptor 100) (GPCR142). |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Cell membrane; Multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | Expressed in a broader range of tissues including brain, kidney, testis, thymus, placenta, prostate, salivary gland, thyroid and colon. |
| Post translational modification | N/A |
| Function | Receptor for relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation. |
| Protein Length | 374 Amino acids |
| Molecular weight | 41141 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 14522967
2 PubMed abstract 14623098
3 PubMed abstract 14530218
4 Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
5 PubMed abstract 12044878
6 PubMed abstract 16710414
7 PubMed abstract 15489334
|
| Hormone | Q8WXF3 Detail in HMRbase
|
| Gene ID | 339403 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | |
A database of hormones and their receptors