A database of hormones and their receptors

Peptide Hormone

HMRbase accession number	10343
Swiss-prot Accession number	Q925Q5 (Sequence in FASTA format)
Description	Glycoprotein hormone alpha-2 precursor (Thyrostimulin subunit alpha).
Source organism	Mus musculus (Mouse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular location	Secreted protein (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the glycoprotein hormones subunit alpha family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Stimulates the thyroid. Binds and activates THSR, leads to increased cAMP production
Protein Length	128 Amino acids
Molecular weight	14030
References	1 Ching A., Gilbert T., Sheppard P., Webster P., O'Hara P.J.; "A novel cysteine knot protein expressed in pancreatic acinar cells."; Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases. 2 PubMed abstract 15489334
Domain Name	N/A
Hormone Name	Glycoprotein hormone alpha-2
Mature Hormone Sequence	HSPETAIPGCHLHPFNVTVRSDRLGTCQGSHVAQACVGHCESSAFPSRYSVLVASGYRHNITSSSQCCTISSLRKVRVWLQCVGNQRGELEIFTARACQCDMCRFSRY
Position of mature hormone in Pre-Hormone protein	108 Residues from position (21-128)
Receptor	P47750 Detail in HMRbase
Gene ID	170458
PDB ID	N/A
Drugpedia	wiki
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