A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 21171 |
| Swiss-prot Accession number | Q96P88 (Sequence in FASTA format) |
| Description | Gonadotropin-releasing hormone II receptor (Type II GnRH receptor)(GnRH-II-R). |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | Expressed in many tissues. |
| Post translational modification | Phosphorylated on the C-terminal cytoplasmic tail (Probable). |
| Function | Receptor for gonadotropin releasing hormone II (GnRH II). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (Potential). |
| Protein Length | 379 Amino acids |
| Molecular weight | 41630 |
| Domain Name | 7tm_1 |
| References | 1 PubMed abstract 11707068 2 PubMed abstract 11861490 |
| Hormone | O43555 Detail in HMRbase |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |