A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21501 |
| Swiss-prot Accession number | Q9PTN2 (Sequence in FASTA format) |
| Description | Vitamin D3 receptor A;VDR-A;Alternative Name: 1,25-dihydroxyvitamin D3 receptor A;Alternative Name: Nuclear receptor subfamily 1 group I member 1-A |
| Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Detected in embryo 24 to 48 hours after fertilization and in gastrula. |
| Post translational modification | N/A |
| Function | Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Plays a central role in calcium homeostasis. |
| Protein Length | 453 Amino acids |
| Molecular weight | 50766 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 17997606 2 PubMed abstract 17346665 3 PubMed abstract 17218092 |
| Hormone | Detail in HMRbase Detail in HMRbase |
| Gene ID | 30076 |
| PDB ID | 2HBH 2HC4 2HCD |
| Drugpedia | wiki |
| Comments |