A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 20019 |
| Swiss-prot Accession number | Q9TU77 (Sequence in FASTA format) |
| Description | Adrenocorticotropic hormone receptor (ACTH receptor) (ACTH-R)(Melanocortin receptor 2) (MC2-R) (Adrenocorticotropin receptor). |
| Source organism | Ovis aries (Sheep) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 1 family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Receptor for ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. |
| Protein Length | 295 Amino acids |
| Molecular weight | 33019 |
| Domain Name | 7tm_1 |
| References | 1 Wang J., Rose J.C.; "Ovine adrenal ACTH receptor: cDNA cloning and developmental changesof mRNA levels."; Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
2 Wang J., Rose J.C.; "Ovine adrenal ACTH receptor: cDNA cloning and developmental changesof mRNA levels."; Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases. |
| Hormone | P01191 Detail in HMRbase |
| Gene ID | 443482 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |