A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 11235 |
| Swiss-prot Accession number | O43555 (Sequence in FASTA format) |
| Description | Progonadoliberin-2 precursor (Progonadoliberin II) [Contains:Gonadoliberin-2 (Gonadoliberin II) (Luteinizing hormone-releasinghormone II) (LH-RH II) (Gonadotropin-releasing hormone II) (GnRH II)(Luliberin II); GnRH-associated peptide 2 (GnRH-associated peptideII)]. |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Secreted protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the GnRH family. |
| Tissue Specificity | Midbrain; expressed at significantly higher levels outside the brain (up to 30-fold), particularly in the kidney, bone marrow and prostate |
| Post translational modification | N/A |
| Function | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones |
| Protein Length | 120 Amino acids |
| Molecular weight | 12918 |
| References | 1 PubMed abstract 9419371 2 PubMed abstract 11780052 3 PubMed abstract 15489334 |
| Domain Name | N/A |
| Hormone Name | Gonadoliberin-2 |
| Mature Hormone Sequence | QHWSHGWYPG |
| Position of mature hormone in Pre-Hormone protein | 10 Residues from position (24-33) |
| Receptor | P30968 Detail in HMRbase Q96P88 Detail in HMRbase |
| Gene ID | 2797 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |