A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 11240 |
| Swiss-prot Accession number | O97655 (Sequence in FASTA format) |
| Description | Progonadoliberin-2 precursor (Progonadoliberin II) [Contains:Gonadoliberin-2 (Gonadoliberin II) (Luteinizing hormone-releasinghormone II) (LH-RH II) (Gonadotropin-releasing hormone II) (GnRH II)(Luliberin II); GnRH-associated peptide 2 (GnRH-associated peptideII)]. |
| Source organism | Macaca mulatta (Rhesus macaque) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
| Subcellular location | Secreted protein (By similarity) |
| Developmental Stage | N/A |
| Similarity | Belongs to the GnRH family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones |
| Protein Length | 114 Amino acids |
| Molecular weight | 12533 |
| References | 1 White R.B., Urbanski H.F., Fernald R.D.; "A second gene for gonadotropin-releasing hormone is expressed in therhesus macaque (Abstract
2 632.18)."; Abstr. - Soc. Neurosci. 24:1609-1609(1998). 3 Abler L.A., Sherwood N.M., Grendell R.L., Golos T.G., Terasawa E.; "cDNA of a second form of luteinizing hormone releasing, chicken LHRH-II, isolated from the non-human primate brain (Abstract 4 632.8)."; Abstr. - Soc. Neurosci. 24:1607-1607(1998). |
| Domain Name | N/A |
| Hormone Name | Gonadoliberin-2 |
| Mature Hormone Sequence | QHWSHGWYPG |
| Position of mature hormone in Pre-Hormone protein | 10 Residues from position (25-34) |
| Receptor | Q8SPZ1 Detail in HMRbase Q95JG1 Detail in HMRbase |
| Gene ID | 619516 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |