A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 11396 |
| Swiss-prot Accession number | P09683 (Sequence in FASTA format) |
| Description | Secretin precursor. |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Secreted |
| Developmental Stage | N/A |
| Similarity | Belongs to the glucagon family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Stimulates formation of NaHCO(3)-rich pancreatic juice and secretion of NaHCO(3)-rich bile and inhibits HCl production by the stomach |
| Protein Length | 121 Amino acids |
| Molecular weight | 13016 |
| References | 1 PubMed abstract 11060443 2 Carlquist M., Joernvall H., Forssmann W.-G., Thulin L., Johansson C.,Mutt V.; "Human secretin is not identical to the porcine/bovine hormone."; IRCS Med. Sci. 13:217-218(1985). |
| Domain Name | Hormone_2 |
| Hormone Name | Secretin |
| Mature Hormone Sequence | HSDGTFTSELSRLREGARLQRLLQGLV |
| Position of mature hormone in Pre-Hormone protein | 27 Residues from position (28-54) |
| Receptor | Q8IV17 Detail in HMRbase P47872 Detail in HMRbase |
| Gene ID | 6343 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |