A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 11455 |
| Swiss-prot Accession number | P41534 (Sequence in FASTA format) |
| Description | Glucagon family neuropeptides precursor [Contains: Growth hormone-releasing factor 1-46 (GRF) (Growth hormone-releasing hormone) (GHRH);Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27)(PACAP27); Pituitary adenylate cyclase-activating polypeptide 38(PACAP-38) (PACAP38)]. |
| Source organism | Gallus gallus (Chicken) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
| Subcellular location | Secreted protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the glucagon family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Primary role of GRF is to release GH from the pituitary |
| Protein Length | 175 Amino acids |
| Molecular weight | 19561 |
| References | 1 PubMed abstract 9022048 2 Yasuhara T., Mizuno K., Somogyvari-Vigh A., Komaki G., Arimura A.; "Isolation and primary structure of chicken PACAP."; Regul. Pept. 37:326-326(1992). |
| Domain Name | Hormone_2 |
| Hormone Name | Growth hormone-releasing factor 1-46 |
| Mature Hormone Sequence | KRHADGIFSKAYRKLLGQLSARNYLHSLMAKRVGGASSGLGDEAEPLS |
| Position of mature hormone in Pre-Hormone protein | 46 Residues from position (83-128) |
| Receptor | Q7ZZJ9 Detail in HMRbase Q309X7 Detail in HMRbase |
| Gene ID | 408251 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |