A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 11508 |
| Swiss-prot Accession number | Q9DG36 (Sequence in FASTA format) |
| Description | Progonadoliberin-2 precursor (Progonadoliberin II) [Contains:Gonadoliberin-2 (Gonadoliberin II) (LHRH II) (Luteinizing hormone-releasing hormone II) (Gonadotropin-releasing hormone II) (GnRH II)(Luliberin II); GnRH-associated peptide 2 (GnRH-associated peptide II)(GAP2)]. |
| Source organism | Rana catesbeiana (Bull frog) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana. |
| Subcellular location | Secreted protein |
| Developmental Stage | Expressed at significantly higher levels during hibernation and post-breeding. Not expressed in pituitary. |
| Similarity | Belongs to the GnRH family. |
| Tissue Specificity | Midbrain and hindbrain |
| Post translational modification | N/A |
| Function | Stimulates the secretion of gonadotropins |
| Protein Length | 93 Amino acids |
| Molecular weight | 10668 |
| References | 1 PubMed abstract 11170016 |
| Domain Name | N/A |
| Hormone Name | Gonadoliberin-2 |
| Mature Hormone Sequence | QHWSHGWYPG |
| Position of mature hormone in Pre-Hormone protein | 10 Residues from position (25-34) |
| Receptor | Q9DE60 Detail in HMRbase Q9DE62 Detail in HMRbase Q9DE63 Detail in HMRbase |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |