A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 10162 |
| Swiss-prot Accession number | Q5EDF9 (Sequence in FASTA format) |
| Description | Thyroliberin precursor [Contains: Prothyroliberin; Thyroliberin(Thyrotropin-releasing hormone) (TRH) (Thyrotropin-releasing factor)(TRF) (TSH-releasing factor) (Protirelin)]. |
| Source organism | Brachydanio rerio (Zebrafish) (Danio rerio) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
| Subcellular location | Secreted protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the TRH family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems |
| Protein Length | 199 Amino acids |
| Molecular weight | 22739 |
| References | 1 Zhang D., Jiang S.; "Molecular cloning and characterization of the thyrotropin-releasinghormone from zebrafish, Danio rerio."; Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
2 Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases. |
| Domain Name | TRH |
| Hormone Name | Thyroliberin |
| Mature Hormone Sequence | QHP |
| Position of mature hormone in Pre-Hormone protein | 3 Residues from position (64-66) |
| Receptor | N/A |
| Gene ID | 266721 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |