A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10191
Swiss-prot Accession numberP87352 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Gamma-melanotropin-like segment; Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Melanotropin beta(Beta-MSH); Beta-endorphin; Met-enkephalin].
Source organismAcipenser transmontanus (White sturgeon)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Chondrostei; Acipenseriformes; Acipenseridae;Acipenser.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionPrecursor protein for pituitary hormones that regulate stress and environmental adaptation
Protein Length263 Amino acids
Molecular weight30163
References1  PubMed abstract 9016801
2  PubMed abstract 9016801
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameMelanotropin beta (Beta-MSH)
Mature Hormone SequenceDGSYKMNHFRWSGPPKD
Position of mature hormone in Pre-Hormone protein17 Residues from position (211-227)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated