A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10197
Swiss-prot Accession numberQ91082 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Gamma-melanotropin-like segment; Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Melanotropin beta(Beta-MSH); Beta-endorphin; Met-enkephalin].
Source organismLepisosteus osseus (Long-nosed gar)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Semionotiformes; Lepisosteidae;Lepisosteus.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionPrecursor protein for pituitary hormones that regulate stress and environmental adaptation
Protein Length259 Amino acids
Molecular weight29675
References1  PubMed abstract 9268621
2  PubMed abstract 9268621
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameBeta-endorphin
Mature Hormone SequenceYGGFMKSWDERSQKPLLTLFKNVIIKDGHQKKGQ
Position of mature hormone in Pre-Hormone protein34 Residues from position (226-259)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated