A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 10235 |
| Swiss-prot Accession number | Q6S9C5 (Sequence in FASTA format) |
| Description | Thymosin beta-4 (T beta-4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)]. |
| Source organism | Chinchilla lanigera (Long-tailed chinchilla) (Chinchilla villidera) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Chinchillidae; Chinchilla. |
| Subcellular location | Cytoplasm (By similarity) |
| Developmental Stage | N/A |
| Similarity | Belongs to the thymosin beta family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. |
| Protein Length | 44 Amino acids |
| Molecular weight | 5053 |
| References | 1 Erdos G., Hu F.Z., Donfack J., Ahmed A.I., Preston R.A., Hayes J.D.,Post J.C., Ehrlich G.D.; "The thymosin beta-4 gene is expressed in chinchilla middle earmucosa."; Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
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| Domain Name | Thymosin |
| Hormone Name | Thymosin beta-4 |
| Mature Hormone Sequence | SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES |
| Position of mature hormone in Pre-Hormone protein | 43 Residues from position (2-44) |
| Receptor | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |