A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10297
Swiss-prot Accession numberP04563 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11832
References1  PubMed abstract 3453895
2  PubMed abstract 6897117
3  PubMed abstract 1701434
Domain NameGastrin  
Hormone NameBig gastrin
Mature Hormone SequenceQLGPQGPQHFIADLSKKQRPPMEEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein34 Residues from position (59-92)
ReceptorP30553    Detail in HMRbase   
Gene ID25320      
PDB IDN/A
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