A database of hormones and their receptors |
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| HMRbase accession number | 10569 |
| Swiss-prot Accession number | P21808 (Sequence in FASTA format) |
| Description | Bombyxin E-1 precursor (BBX-E1) (Bombyxin IV) (4K-prothoracicotropichormone IV) (4K-PTTH-IV) [Contains: Bombyxin E-1 B chain; Bombyxin E-1A chain]. |
| Source organism | Bombyx mori (Silk moth) |
| Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx. |
| Subcellular location | Secreted protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the insulin family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | PTTH is a brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects |
| Protein Length | 98 Amino acids |
| Molecular weight | 10987 |
| References | 1 PubMed abstract 9253178 2 Maruyama K., Hietter H., Nagasawa H., Isogai A., Tamura S., Suzuki A.,Ishizaki H.; "Isolation and primary structure of bombyxin-IV, a novel molecularspecies of bombyxin from the silkworm, Bombyx mori."; Agric. Biol. Chem. 52:3035-3041(1988). 3 PubMed abstract 1515030 |
| Domain Name | Insulin |
| Hormone Name | Bombyxin E-1 A chain |
| Mature Hormone Sequence | GVVDECCIQPCTLDVLATYC |
| Position of mature hormone in Pre-Hormone protein | 20 Residues from position (79-98) |
| Receptor | N/A |
| Gene ID | 100146109 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |