A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 10666 |
| Swiss-prot Accession number | Q09169 (Sequence in FASTA format) |
| Description | Glucagon family neuropeptides precursor [Contains: Growth hormone-releasing factor (GRF) (Growth hormone-releasing hormone) (GHRH);Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27)(PACAP27); Pituitary adenylate cyclase-activating polypeptide 38(PACAP-38) (PACAP38)]. |
| Source organism | Rana ridibunda (Laughing frog) (Marsh frog) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Pelophylax. |
| Subcellular location | Secreted protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the glucagon family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | PACAP plays pivotal roles as a neurotransmitter and/or a neuromodulator. Stimulates adenylate cyclase in pituitary cells |
| Protein Length | 171 Amino acids |
| Molecular weight | 19680 |
| References | 1 PubMed abstract 10813784 2 PubMed abstract 1720095 |
| Domain Name | Hormone_2 |
| Hormone Name | Pituitary adenylate cyclase-activating polypeptide 27 |
| Mature Hormone Sequence | HSDGIFTDSYSRYRKQMAVKKYLAAVL |
| Position of mature hormone in Pre-Hormone protein | 27 Residues from position (127-153) |
| Receptor | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |