A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 10780 |
| Swiss-prot Accession number | P37240 (Sequence in FASTA format) |
| Description | Thyrotropin subunit beta precursor (Thyroid-stimulating hormonesubunit beta) (TSH-beta) (TSH-B) (Thyrotropin beta chain). |
| Source organism | Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
| Subcellular location | Secreted protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the glycoprotein hormones subunit beta family. |
| Tissue Specificity | Pituitary gland. Higher levels seen in immature fishes than the mature fishes |
| Post translational modification | N/A |
| Function | Indispensable for the control of thyroid structure and metabolism. May play some role in the biological processes of the immature fishes |
| Protein Length | 147 Amino acids |
| Molecular weight | 16440 |
| References | 1 PubMed abstract 8327483 |
| Domain Name | Cys_knot |
| Hormone Name | Thyroid-stimulating hormone subunit beta (TSH-B) (Thyrotropin beta chain) |
| Mature Hormone Sequence | MCVPTDYTLYEERRECDFCVAINTTICMGFCYSRDSNMKELAGPRFLIQRGCTYDQVEYRTVILPGCPLHANPLFTYPVALSCHCGTCNTDSDECAHKASSGDGARCSKPLRHIYPYPGLNSYIHPN |
| Position of mature hormone in Pre-Hormone protein | 127 Residues from position (21-147) |
| Receptor | N/A |
| Gene ID | 100136289 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |