A database of hormones and their receptors |
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| HMRbase accession number | 10890 |
| Swiss-prot Accession number | P21563 (Sequence in FASTA format) |
| Description | Insulin precursor [Contains: Insulin B chain; Insulin A chain]. |
| Source organism | Rodentia sp. |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;unclassified rodents. |
| Subcellular location | Secreted. Note=Stored in spherulous cells prior to secretion |
| Developmental Stage | N/A |
| Similarity | Belongs to the insulin family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver |
| Protein Length | 108 Amino acids |
| Molecular weight | 11849 |
| References | 1 PubMed abstract 2531072 2 Bairoch A., Duret L.; Unpublished observations (FEB-1996). 3 Mueller W.E.G.; Unpublished observations (APR-1996). |
| Domain Name | Insulin |
| Hormone Name | Insulin A chain |
| Mature Hormone Sequence | IVQQCTSGICSLYQENYCN |
| Position of mature hormone in Pre-Hormone protein | 19 Residues from position (90-108) |
| Receptor | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |