A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 10905 |
| Swiss-prot Accession number | Q9W7R2 (Sequence in FASTA format) |
| Description | Insulin precursor [Contains: Insulin B chain; Insulin A chain]. |
| Source organism | Verasper moseri (Barfin flounder) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Pleuronectiformes;Pleuronectoidei; Pleuronectidae; Verasper. |
| Subcellular location | Secreted |
| Developmental Stage | N/A |
| Similarity | Belongs to the insulin family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver |
| Protein Length | 115 Amino acids |
| Molecular weight | 12608 |
| References | 1 Andoh T., Nagasawa H.; "Two molecular forms of insulin from barfin flounder, Verasper moseri,are derived from a single gene."; Zool. Sci. 15:931-937(1998).
|
| Domain Name | Insulin |
| Hormone Name | Insulin A chain |
| Mature Hormone Sequence | GIVEQCCHKPCNIFDLQNYCN |
| Position of mature hormone in Pre-Hormone protein | 21 Residues from position (95-115) |
| Receptor | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |