A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 10915 |
| Swiss-prot Accession number | P01175 (Sequence in FASTA format) |
| Description | Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin(Ocytocin); Neurophysin 1]. |
| Source organism | Bos taurus (Bovine) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
| Subcellular location | Secreted |
| Developmental Stage | N/A |
| Similarity | Belongs to the vasopressin/oxytocin family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland |
| Protein Length | 125 Amino acids |
| Molecular weight | 12665 |
| References | 1 PubMed abstract 3768139 2 PubMed abstract 6709064 3 PubMed abstract 6209133 4 PubMed abstract 13129273 5 Tuppy H., Michl H.; "About the chemical structure of oxytocin."; Monatsh. Chem. 84:1011-1020(1953). 6 PubMed abstract 670174 7 PubMed abstract 428540 8 PubMed abstract 2911588 9 PubMed abstract 3008332 |
| Domain Name | Hormone_5 |
| Hormone Name | Oxytocin |
| Mature Hormone Sequence | CYIQNCPLG |
| Position of mature hormone in Pre-Hormone protein | 9 Residues from position (20-28) |
| Receptor | P56449
Detail in HMRbase |
| Gene ID | 280888 |
| PDB ID | 1L5C 1L5D 1XY1 1XY2 2HNU 2HNV 2HNW |
| Drugpedia | wiki |
| Comments |