A database of hormones and their receptors |
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| HMRbase accession number | 11048 |
| Swiss-prot Accession number | P63313 (Sequence in FASTA format) |
| Description | Thymosin beta-10. |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Cytoplasm |
| Developmental Stage | Found to decrease dramatically after birth. |
| Similarity | Belongs to the thymosin beta family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization |
| Protein Length | 44 Amino acids |
| Molecular weight | 5026 |
| References | 1 PubMed abstract 3365256 2 PubMed abstract 2169566 3 PubMed abstract 8425765 4 Condon M.R., Hall A.K.; "Human thymosin beta 10 gene: its characterization and nucleotidesequence."; Submitted (APR-1992) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 15489334 6 PubMed abstract 16916647 |
| Domain Name | Thymosin |
| Hormone Name | Thymosin beta-10 |
| Mature Hormone Sequence | ADKPDMGEIASFDKAKLKKTETQEKNTLPTKETIEQEKRSEIS |
| Position of mature hormone in Pre-Hormone protein | 43 Residues from position (2-44) |
| Receptor | N/A |
| Gene ID | 9168 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |