A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 11069 |
| Swiss-prot Accession number | P01278 (Sequence in FASTA format) |
| Description | Glucagon-1 precursor (Glucagon I) [Contains: Glicentin-relatedpolypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1(Glucagon-like peptide I)]. |
| Source organism | Lophius americanus (American goosefish) (Anglerfish) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Paracanthopterygii; Lophiiformes; Lophiidae; Lophius. |
| Subcellular location | Secreted |
| Developmental Stage | N/A |
| Similarity | Belongs to the glucagon family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. |
| Protein Length | 124 Amino acids |
| Molecular weight | 14165 |
| References | 1 PubMed abstract 7043459 2 PubMed abstract 6165720 3 PubMed abstract 3058456 |
| Domain Name | Hormone_2 |
| Hormone Name | Glucagon-1 |
| Mature Hormone Sequence | HSEGTFSNDYSKYLEDRKAQEFVRWLMNN |
| Position of mature hormone in Pre-Hormone protein | 29 Residues from position (53-81) |
| Receptor | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |